Aadya Diagnostics Centre is the best centre for VDRL Tests. VDRL is an abbreviation for the Venereal Disease Research Laboratory test. It is an example of a Slide flocculation test that is used for serological diagnosis of syphilis. Cardiolipin antigen is utilised as a reagent in this test to detect auto-antibody in patient serum. Cardiolipin antigen is an alcoholic extract of the bovine heart muscle that has been supplemented with lecithin and cholesterol. Cardiolipin autoantibodies (IgM and IgG) react non-specifically with cardiolipin to create flocculation (floccular agglutination). Due to tissue damage, autoantibodies in reaction to cardiolipin are formed within 2-3 weeks of treponemal infection. The mitochondrial membrane is the antigen that stimulates autoantibody formation. These autoantibodies are capable of reacting with cardiolipin.
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